The land belonging to the Priory in Cantenac, which was founded by the monks from Vertheuil Abbey in the Romanesque period, was used for mixed farming and livestock, with some plots devoted to the production of wines that were already recognized for their quality. It was not until the middle of the 18th century that the entire property was planted with vines. The Priory's wine was ranked at that time as a third growth by the Intendance de Bordeaux in the classification of the parishes of Margaux and Cantenac. After the French Revolution, the property was acquired by Monsieur Durand Delains, a Bordeaux wine merchant. Promoted to a fourth growth in the 1855 Classification, the property then underwent a series of crises with phylloxera and then the crash of 1929. When Alexis Lichine, known as the Wine Pope, purchased it in the early 1950s, the vineyard was in a pitiable state. He devoted himself to restoring the property until his death in 1989. Today, Château Prieuré Lichine is owned by the Ballande group, assisted by consultant oenologist Stéphane Derenoncourt.

Château Prieuré Lichine's second wine is matured for 12 to 16 months in the barrel, 40% for one wine and 60% for two wines. It is typical of the appellation with its aromas of well matured dark fruit and its light notes of élevage and supple and fruity palate.